What is Osteoarthritis?

Osteoarthritis (OA), sometimes called degenerative joint disease, is the most common form of arthritis. Osteoarthritis occurs when the cartilage in your joints wears down over time. This loss of cartilage allows bones to rub together, causing pain, swelling, and loss of motion of the joint. Osteoarthritis gradually worsens with time, and no cure is known. Osteoarthritis treatments, however, can relieve pain and help you remain active.

What is Electrosonic Stimulation (ESStim™)?

ESStim™, a novel technology, currently under development at Highland, is capable of noninvasive focal and deep brain stimulation. Highland is developing ESStim™ to treat osteoarthritis (OA) patients suffering from chronic pain, by stimulating the brain and blocking the processing of the pain signal originating at the affected joint.

How does ESStim™ work in the treatment of chronic pain?

Chronic pain resulting from OA is characterized by a phenomenon known as central sensitization, whereby the brain adapts to become more receptive to pain signals. By targeting ESStim™ to select regions of the brain, evidence suggests a blocking of pain signals, providing patients with persistent therapeutic relief.

Where can I get further information about Osteoarthritis?

The following links provide useful information for patients: